ChEMBL

The ChEMBL connector gives Claude access to the ChEMBL Database, a manually curated resource of bioactive drug-like compounds with quantitative binding and functional data against biological targets. Search for compounds by name or structure, retrieve bioactivity data (IC50, EC50, Ki values), find drug targets and mechanisms of action, access ADMET properties, and discover approved drugs by indication.

You can use the ChEMBL connector to:

Research a Drug Target: "I'm interested in EGFR inhibitors. What are the IC50 values of gefitinib and erlotinib against EGFR?"

Explore Drug Repurposing: "Find approved drugs that target BCR-ABL. I want to explore repurposing opportunities."

Assess Lead Compound Properties: "I have a compound with ChEMBL ID CHEMBL123456. What are its drug-like properties and how potent is it?"