Synthesize Bio

Synthesize Bio lets Claude generate and analyze gene expression data from a virtual human from a natural language prompt. Describe any experiment — "tumor vs normal lung tissue" or "KRAS knockout vs control" — and the platform generates realistic human expression profiles using its Gene Expression Model (GEM). You can use this gene expression data just as if you had done a laboratory experiment on human samples. Supports both bulk and single-cell RNA-seq modalities. See https://www.synthesize.bio/ to learn more about virtual humans, GEM, and to register for an account.

You can use Synthesize Bio to:

Analyze tumor vs normal tissue:
"Use the Synthesize Bio connector to analyze lung adenocarcinoma tumor vs normal lung tissue."

Compare cell types in single-cell mode:
"Analyze CD4+ T cells vs CD8+ T cells in single-cell RNA-seq mode using Synthesize Bio."

Compare drug toxicity signatures:
"Use Synthesize Bio to predict how hepatocytes respond to doxorubicin vs. valproic acid and compare their toxicity signatures."

Find druggable targets:
"Use Synthesize Bio to find druggable targets in idiopathic pulmonary fibrosis by comparing fibrotic vs. healthy alveolar epithelial cells."